Microwave Assisted Synthesis and Characterization of Silver Nanoparticles Using Citrullus Lanatus Leaf Extract and Its Anti-Inflammatory Activity Against Human Blood Cells
P. Anitha1, P. Sakthivel2

1P. Anitha, Assistant Professor, Department of Physics, Roever College of Engineering and Technology, Perambalur, Tamil Nadu, India.
2P. Sakthivel, Associate Professor, Department of Physics, Urumu Dhanalakshmi College, Trichy, Tamil Nadu, India.
Manuscript received on April 01, 2016. | Revised Manuscript received on April 06, 2016. | Manuscript published on April 30, 2016. | PP: 1-6 | Volume-3 Issue-3, April 2016. | Retrieval Number: C0363043316
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© The Authors. Published By: Blue Eyes Intelligence Engineering and Sciences Publication (BEIESP). This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)

Abstract: The use of engineered nanomaterials has increased as a result of their positive impact on many sectors of the economy, including agriculture. In the current study, the plant extract of Citrullus Lanatus is used for the synthesis of silver nanoparticles. The leaf extract is mixed with AgNO3 , and then it is incubated. The extract is kept in microwave oven for exposure of heat, then it is dried and powdered. The synthesized dried powder is confirmed as nanoparticles by color transformation. The characterization of silver nanoparticles was studied by UV–Vis spectroscopy, FTIR, XRD& TEM. The silver nanoparticles synthesized were generally found in size 1-100 nm. The average size of synthesized silver nanoparticles is found to be 15.98 nm using XRD data by Scherrer’s formula, which is approximately similar as the size obtained in TEM Analysis 16.32 nm. In totality, the AgNPs prepared are safe to be discharged in the environment and possibly utilized in processes of pollution remediation. AgNPs may also be efficiently utilized in Anti-inflammatory activity of Pharmaceutical research to obtain better result of plant as shown by our study. The Anti-inflammatory activity of silver nanoparticles was tested on human blood cells which confirms that the plant mediated synthesis of silver nanoparticles have a significant Anti-inflammatory effect on human blood cells.
Keywords: Silver Nanoparticles, UV–Vis Spectroscopy, FTIR, TEM, XRD, Anti-Inflammatory, Human Blood Cells, etc.