Simulation of Voltage Change Effects in Ion Channels in order to Reproduction of Action Potential by MATLAB Software
Mostafa Mohammadi1, Alireza Kashani Nia2
1Mostafa Mohammadi, Graduated in of Electronic Engineering, Department of Electrical Engineering, Islamic Azad University,Central Tehran Branch, Tehran, Iran.
2Dr. Alireza Kashani Nia, Ph.d in Electronic Engineering. Department of Electrical Engineering, Islamic Azad University, Central Tehran Branch, Tehran, Iran.

Manuscript received on May 02, 2015. | Revised Manuscript received on May 09, 2015. | Manuscript published on May 31, 2015. | PP: 1-6 | Volume-2 Issue-6, May 2015. | Retrieval Number: F0295052615
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Abstract: In this study, the effects of voltage change in ion channels in order to reproduction of action potential and its simulation by Hodgkin Huxley model have been explored . The simulation has been performed by using the Matlab software . By writing Hodgkin Huxley equations codes and applying the parameters values of it , action potential waveform to obtain. Then by reducing the amount of excitation current, the lowest value that the action potential is placed on the eve of the production will be obtain. The next step is to stabilize the input excitation current to the value obtained and then change the sudiom , potasiom and leakage channels voltage. According to the characteristics of each ion channels and voltage variations on them, action potential will start to reproduce. Thus we have shown, with the decline of the excitation current for reasons such as some illness, we can reproduce the action potential and propagate it inside of axon by changing the ion channels voltage.
Keywords: Action potential, Axon, Hodgkin Huxley model, Excitation current, Matlab simulation.